Dr. Sofia Bashir Mohamed Ali
Associate Professor of Molecular Biology and Bioinformatics – , Director & Co-founder of the National University Biomedical Research Institute (NUBRI)
Position
Associate Professor of Molecular Biology and Bioinformatics – , Director & Co-founder of the National University Biomedical Research Institute (NUBRI)
Biography
Biography: Dr. Sofia Ali is a distinguished Associate Professor with over 15 years of experience in research, education, and institutional leadership. She played a foundational role in establishing NUBRI as a national center of excellence in pathogen genomics, computational biology, and molecular diagnostics. Her expertise includes next-generation sequencing (NGS), structural bioinformatics, antimicrobial resistance (AMR), and computational drug design. Under her visionary leadership, NUBRI has become a transformative force in Sudan’s biomedical landscape—particularly in genetic bioinformatics and computational biology. She has led the launch of postgraduate programs in bioinformatics and genetics and has been instrumental in building national capacity in advanced biomedical research. Dr. Ali continues to champion cross-border collaboration and scientific innovation, addressing pressing health challenges in both stable and crisis-affected regions.
Research Interests
- Dr. Sofia Ali specializes in genomics, molecular epidemiology, and computational drug discovery, with a focus on whole-genome sequencing, antimicrobial resistance, and cancer biomarker discovery. Her work integrates structural bioinformatics—including protein modeling and molecular simulations—with large-scale data analysis using R, Linux, and Galaxy. She applies translational bioinformatics to support diagnostics, vaccine design, and therapeutic target discovery, particularly for infectious diseases.
Notable Achievements
- Co-Founder and Director of NUBRI (Sudan).
- Pioneer of Sudan’s First COVID-19 Molecular Diagnostic Lab (2020)
- Designed and launched Sudan’s Master’s and PhD programs in Bioinformatics and Molecular Genetics.
- Initiated and launched NUBRI Galaxy, a national platform to expand local capacity in NGS data analysis and bioinformatics training.
- Successfully mentored over 50 MSc and PhD students in areas including genomics, AMR, and cancer research.
- International Recognition. Awarded several prestigious fellowships, including: DAR Fellowship (Qatar), IIE-SRF Fellowship (USA), ASLP Fellowship (Africa Science Leadership Program)
Collaborations
- African BioGenome Project (2021–2031) – NUBRI serves as Sudan’s national node, contributing to genomics, biodiversity, and public health research.
- DAR Fellowship Project (Qatar University, 2025–2028) – "Discovery of Novel Avicennia marina-Derived Molecules Targeting the BRCA1/BARD1 Complex in Breast Cancer."